Editor-in-chief: Gian Paolo Andreoletti, MD

Connecting Specialists Worldwide

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Literature Selection

• Mohr SB et al.: "Serum 25-hydroxyvitamin d and prevention of breast cancer: pooled analysis", Anticancer Res. 2011 Sep;31(9):2939-48
• Dong JY et al.: "Dietary fiber intake and risk of breast cancer: a meta-analysis of prospective cohort studies", Am J Clin Nutr. 2011 Sep;94(3):900-5
• Bosco JL et al.: "Regular aspirin use and breast cancer risk in US Black Women", Cancer Causes Control. 2011 Aug 30. [Epub ahead of print]
• Hardman WE et al.: "Dietary Walnut Suppressed Mammary Gland Tumorigenesis in the C(3)1 TAg Mouse", Nutr Cancer. 2011 Aug-Sep;63(6):960-70
• Cybulski C et al.: "Risk of Breast Cancer in Women With a CHEK2 Mutation With and Without a Family History of Breast Cancer", J Clin Oncol. 2011 Aug 29. [Epub ahead of print]
• Niikura N et al.: "FDG-PET/CT Compared with Conventional Imaging in the Detection of Distant Metastases of Primary Breast Cancer", Oncologist. 2011;16(8):1111-9
• Kiess AP et al.: "Adjuvant trastuzumab reduces locoregional recurrence in women who receive breast-conservation therapy for lymph node-negative, human epidermal growth factor receptor 2-positive breast cancer", Cancer. 2011 Sep 1. doi: 10.1002/cncr.26484. [Epub ahead of print]
• Chen JH et al.: "Breast Cancer: Evaluation of Response to Neoadjuvant Chemotherapy with 3.0-T MR Imaging", Radiology. 2011 Aug 30. [Epub ahead of print]
• Howard-McNatt M et al.: "Contralateral prophylactic mastectomy in breast cancer patients who test negative for BRCA mutations", Am J Surg. 2011 Sep;202(3):298-302
• Bagaria SP et al.: "Prognostic Value of Basal Phenotype in HER2-overexpressing Breast Cancer", Ann Surg Oncol. 2011 Aug 31. [Epub ahead of print]

Discussion

• Christiansen P et al.: "Mortality Rates Among Early-Stage Hormone Receptor-Positive Breast Cancer Patients: A Population-Based Cohort Study in Denmark", J Natl Cancer Inst. 2011 Aug 31. [Epub ahead of print]

  • "Is adjuvant endocrine therapy necessary for older breast cancer patients with hormone-responsive early-stage tumors?" - Share your opinion on  LinkedIn®. 

Comment

• "Benefit of  single-injection Depot Progesterone before surgery in node positive breast cancer patients" - Raj Badwe, Tata Memorial Hospital, Mumbai, India
   
  "This is the first randomized evidence suggesting benefit of short-term peri-operative hormone therapy (progesterone) in DFS and OS in node positive breast cancer. The results not only suggest an easily implementable cost-effective intervention in routine clinical practice but also offers some biological insights about when does metastases set in? and how modulation of events at the time of surgery affects a chronic disease? In absence of side effects and low cost of intervention this would be the most effective intervention for the developing world as well as cash strapped health care systems globally. The results need to be reproduced in other parts of the world"  
  (Comment on:  Badwe R et al.: "Single-Injection Depot Progesterone Before Surgery and Survival in Women With Operable Breast Cancer: A Randomized Controlled Trial", J Clin Oncol. 2011 Jul 20;29(21):2845-51)

Fragments of History

• Richard Volkmann, "Beitrage zur Chirurgie", Leipzig, Germany (1875):  “I make it a rule never to do a partial amputation for cancer of the breast, but remove the entire breast even for the smallest tumors, and at the same time I take away a liberal piece of skin. The skin defect  is, of course, very great when one operates in this manner, and the wound, in consequence, requires a long time for healing. Furthermore, in making the lower incision I cut right down to the pectoralis muscle and clean its fibres, as I would for a class-room dissection, carrying the knife parallel with the muscular fasciculi and penetrating into their interstices. The fascia of the muscle is,accordingly, entirely removed. I was led to adopt this procedure because, on microscopical examination, I repeatedly found when I had not expected it that the fascia was already carcinomatous,whereas the muscle was certainly not involved. (…). It seems to me, therefore, that the fascia serves for a time as a barrier, and is able to bring to a halt the spreading growth of the carcinoma"

Calendar of Events

• Breast Cancer Symposium 2011, September 8-10, 2011, San Francisco, California
• 7th Meet the Professor.  Modena International Breast Cancer Conference (MIBCC)
  October 5-7, 2011, Modena, Italy - under the Patronage of Senology.org
• 1st Advanced Breast Cancer International Consensus Conference, November 3-5, 2011, Lisbon, Portugal
• 33^rd Congress of the French Senologic Society November 9-11, 2011 Marseille France
• AORTIC (African Organisation for Research and Training in Cancer) - 8th International Conference, November 28 - December 2, 2011, Cairo, Egypt

Literature Selection

• Takahashi Y et al.: "Fibrous stroma is associated with poorer prognosis in lung squamous cell carcinoma patients", J Thorac Oncol. 2011 Sep;6(9):1460-7
• Gibson TM et al.: "Pre- and postfortification intake of folate and risk of colorectal cancer in a large prospective cohort study in the United States", Am J Clin Nutr. 2011 Sep, ajcn. 002659
• Ma Y et al.: "Association Between Vitamin D and Risk of Colorectal Cancer: A Systematic Review of Prospective Studies", J Clin Oncol. 2011 Aug 29. [Epub ahead of print]
• Aune D et al.: "Body mass index, abdominal fatness and pancreatic cancer risk: a systematic review and non-linear dose-response meta-analysis of prospective studies", Ann Oncol. 2011 Sep 2. [Epub ahead of print]
• Tang JY et al.: "Menopausal Hormone Therapy and Risks of Melanoma and Nonmelanoma Skin Cancers: Women's Health Initiative Randomized Trials", J Natl Cancer Inst. 2011 Aug 30. [Epub ahead of print]
• Darefsky AS et al.: "Adult glioblastoma multiforme survival in the temozolomide era: A population-based analysis of surveillance, epidemiology, and end results registries", Cancer. 2011 Aug 31. doi: 10.1002/cncr.26494. [Epub ahead of print]