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Literature Selection

• Venturini E et al.: "Tailored Breast Cancer Screening Program with Microdose Mammography, US, and MR Imaging: Short-term Results of a Pilot Study in 40-49-Year-Old Women", Radiology. 2013 Apr 11. [Epub ahead of print]
• Girardi V et al.: "Breast ultrasound in 22,131 asymptomatic women with negative mammography", Breast. 2013 Apr 1 [Epub ahead of print]
• Nelson H et al.: "Use of medications to reduce risk for primary breast cancer: a systematic review for the u.s. Preventive services task force", Ann Intern Med. 2013 Apr 16;158(8):604-14
• Heemskerk-Gerritsen BA et al.: "Substantial breast cancer risk reduction and potential survival benefit after bilateral mastectomy when compared with surveillance in healthy BRCA1 and BRCA2 mutation carriers: a prospective analysis", Ann Oncol. 2013 Apr 10. [Epub ahead of print]
• Li J et al.: "Mammographic Density Reduction Is a Prognostic Marker of Response to Adjuvant Tamoxifen Therapy in Postmenopausal Patients With Breast Cancer", J Clin Oncol. 2013 Apr 22. [Epub ahead of print]
• Lazzeroni M et al.: "Tailoring treatment for ductal intraepithelial neoplasia of the breast according to Ki-67 and molecular phenotype", Br J Cancer. 2013 Apr 11 [Epub ahead of print]
• Zagouri F et al.: "Intrathecal administration of trastuzumab for the treatment of meningeal carcinomatosis in HER2-positive metastatic breast cancer: a systematic review and pooled analysis", Breast Cancer Res Treat. 2013 Apr 16. [Epub ahead of print]
• Chen X et al.: "Analysis in early stage triple-negative breast cancer treated with mastectomy without adjuvant radiotherapy: Patterns of failure and prognostic factors", Cancer. 2013 Apr 10. doi: 10.1002/cncr.28085. [Epub ahead of print]

Questions and Answers 

• Breast Cancer Workshop Summary - with Cynthia Ma, Washington University School of Medicine, St. Louis, MO, USA

Discussion

•   "Even in women with breast tumours of excellent prognosis, local recurrence after conservative surgery without adjuvant therapy is very high " -  Share your opinion on LinkedIn

Fragments of History

• 1981 - Umberto Veronesi, National Cancer Institute, Milan, Italy: "A number of different factors may explain the progressive development of new procedures for conservative treatment of breast cancer. The first factor is a better understanding of the natural history of breast cancer and of the fact that the results of treatment are influenced more by distant spread when it occurs than by local or regional control of the disease. The second is the discovery of increasing numbers of cancers of minimal dimensions by means of new diagnostic techniques, especially mammography. The third is the more pressing demand for less mutilating procedures and the increasing requests from patients to be informed of the various possible treatments, including the conservative techniques. Finally, there is a widespread belief that if a conservative treatment could be offered to women with early breast cancer, it would represent a tremendous tool for publicizing self-examination of the breasts and alertness in seeking medical advice at the first appearance of a lump in the breast". (Veronesi U et al.: "Comparing radical mastectomy with quadrantectomy, axillary dissection, and radiotherapy in patients with small cancers of the breast", N Engl J Med.1981Jul 2;305(1):6-11)

Calendar of Events

• 5th IMPAKT Breast Cancer Conference, May 2-4, 2013, Brussels, Belgium
• Precision Medicines in Breast Cancer, May 9-10, 2013, London, UK
• 15th Milan Breast Cancer Conference, June 20-21, 2013, Milan, Italy
• 3rd World Congress on Cancer Science & Therapy, October 21-23, 2013,  San Francisco, CA, USA - in Partnership with Senology
• 9th Meet the Professor. Advanced International Breast Cancer Conference (AIBCC), November 11-13, Padova, Italy - under the Patronage of Senology
• Update in Breast Imaging, 22-23 November, Ostend, Belgium

Literature Selection

• Su VY et al.: "Amiodarone and the risk of cancer: A nationwide population-based study", Cancer. 2013 Apr 8. doi: 10.1002/cncr.27881. [Epub ahead of print]
• Raaschou P et al.: "Rheumatoid arthritis, anti-tumour necrosis factor therapy, and risk of malignant melanoma: nationwide population based prospective cohort study from Sweden", BMJ. 2013 Apr 8;346:f1939
• Xing M et al.: "Association between BRAF V600E mutation and mortality in patients with papillary thyroid cancer", JAMA. 2013 Apr 10;309(14):1493-501
• Dorffel W et al.: "Treatment of Children and Adolescents With Hodgkin Lymphoma Without Radiotherapy for Patients in Complete Remission After Chemotherapy: Final Results of the Multinational Trial GPOH-HD95", J Clin Oncol. 2013 Apr 20;31(12):1562-8

Editorial

•  "Core needle biopsy for thyroid nodules with previous non-diagnostic fine needle aspiration", Jung Hwan Baek,  Department of Radiology and Research Institute of Radiology, University of Ulsan College of Medicine, Asan Medical Center, Seoul, Korea
   
  "Core needle biopsy (CNB) for thyroid nodules with previous non-diagnostic fine needle aspiration (FNA) results showed a low incidence (1.3%, 2/155) of non-diagnostic results. CNB also showed high diagnostic values for neoplasm and malignancy. In addition, CNB could prevent unnecessary diagnostic surgery in 96% (22 of 23) of patients with repeated nondiagnostic FNA results. This result suggests that CNB is a viable method of choice for the reliable diagnosis of thyroid nodules for which previous FNA results were nondiagnostic"
  (Commentary on:  Yeon JS et al.: "Thyroid Nodules with Initially Nondiagnostic Cytologic Results: The Role of Core-Needle Biopsy", Radiology 2013 Mar 22 [Epub ahead of print])

Questions and Answers 

• Kidney Cancer Workshop Summary - with Sumanta Kumar, City of Hope, Duarte, CA, USA
• Lung Cancer Workshop Summary - with Jared Weiss, University of North Carolina, Chapel Hill, NC, USA
• Stem Cell Workshop Summary - with Anthony Stein, City of Hope, Duarte, CA, USA