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Literature Selection

• Lee B et al.: "The efficacy of axillary ultrasound in the detection of nodal metastasis in breast cancer", AJR Am J Roentgenol. 2013 Mar;200(3):W314-20
• Witzel I et al.: "Androgen receptor expression is a predictive marker in chemotherapy-treated patients with endocrine receptor-positive primary breast cancers", J Cancer Res Clin Oncol. 2013 Feb 8. [Epub ahead of print]
• Narod SA et al.: "Should all BRCA1 mutation carriers with stage I breast cancer receive chemotherapy?", Breast Cancer Res Treat. 2013 Feb 6. [Epub ahead of print]
• Xu Y et al.: "Promoter methylation of BRCA1 in triple-negative breast cancer predicts sensitivity to adjuvant chemotherapy", Ann Oncol. 2013 Feb 13. [Epub ahead of print]
• Hertz DL et al.: "CYP2C8*3 increases risk of neuropathy in breast cancer patients treated with paclitaxel", Ann Oncol. 2013 Feb 14. [Epub ahead of print]
• Boccardo F et al.: "Switching to anastrozole versus continued tamoxifen treatment of early breast cancer: Long term results of the Italian Tamoxifen Anastrozole trial", Eur J Cancer. 2013 Feb 14 [Epub ahead of print]
• Botteri E et al.: "Role of breast surgery in T1-3 breast cancer patients with synchronous bone metastases", Breast Cancer Res Treat. 2013 Feb 15. [Epub ahead of print]
• Grantzau T et al.: "Second primary cancers after adjuvant radiotherapy in early breast cancer patients: A national population based study under the Danish Breast Cancer Cooperative Group, Radiother Oncol. 2013 Feb 7 [Epub ahead of print]
• Sakurai T et al.: "Long-term follow-up of nipple-sparing mastectomy without radiotherapy: a single center study at a Japanese institution", Med Oncol. 2013 Mar;30(1):481
• Zambetti A et al.: "Bone Mineral Density is a Prognostic Factor for Postmenopausal Caucasian Women with Breast Cancer", Breast J. 2013 Feb 13 [Epub ahead of print]

Questions and Answers 

• Breast Cancer Workshop Summary - with Kevin Kalinsky, New York-Presbyterian Hospital/Columbia University Medical Center, New York, NY, USA

Fragments of History

• 1968 - Bernard Fisher, Department of Surgery, University of Pittsburgh, Pittsburgh, PA, USA: "The Halsted radical mastectomy, first described in 1894, is a local form of therapy for mammary cancer which, by itself, can cure only those patients whose tumor is confined to the tissues of the chest wall and axilla removed at surgery. Observation in this study of a 5-year recurrence rate of 20 per cent in patients with negative nodes and close to 70 per cent in those with positive nodes emphasizes the inability of conventional radical surgery to eradicate all cancer cells because of their dissemination prior to or at the time of operation. More extensive regional dissection, carried to the limit of feasibility and sensibility, has not produced a substantial improvement in results". (Fisher B et al.: "Surgical adjuvant chemotherapy in cancer of the breast: results of a decade of cooperative investigation", Ann Surg. 1968 Sep;168(3):337-56)

Calendar of Events

• 13th St. Gallen International Breast Cancer Conference, March 13-16, 2013, St. Gallen, Switzerland
• 5th IMPAKT Breast Cancer Conference, May 2-4, 2013, Brussels, Belgium
• Precision Medicines in Breast Cancer, May 9-10, 2013, London, UK
• 15th Milan Breast Cancer Conference, June 20-21, 2013, Milan, Italy
• 3rd World Congress on Cancer Science & Therapy, October 21-23, 2013,  San Francisco, CA, USA
• 9th Meet the Professor. Advanced International Breast Cancer Conference (AIBCC), November 11-13, Padova, Italy - under the Patronage of Senology.org
• Update in Breast Imaging, 22-23 November, Ostend, Belgium

Literature Selection

• Lee JH et al.: "The association between papillary thyroid carcinoma and histologically proven Hashimoto's thyroiditis: a meta-analysis", Eur J Endocrinol 2013 Feb 15; 168(3):343-9
• Roguin  et al.: "Brain and Neck Tumors Among Physicians Performing Interventional Procedures", Am J Cardiol. 2013 Feb 16 [Epub ahead of print]
• Henschke CI et al.: "Definition of a positive test result in computed tomography screening for lung cancer: a cohort study", Ann Intern Med. 2013 Feb 19;158(4):246-52
• Guarner-Argente C et al.: "Long-term outcomes of patients with Barrett's esophagus and high-grade dysplasia or early cancer treated with endoluminal therapies with intention to complete eradication", Gastrointest Endosc. 2013 Feb;77(2):190-9
• van der Pas MH et al.: "Laparoscopic versus open surgery for rectal cancer (COLOR II): short-term outcomes of a randomised, phase 3 trial", Lancet Oncol. 2013 Feb 5 [Epub ahead of print]
• Ho AL et al.: "Selumetinib-enhanced radioiodine uptake in advanced thyroid cancer", N Engl J Med. 2013 Feb 14;368(7):623-32
• Martin V et al.: "HER2 gene copy number status may influence clinical efficacy to anti-EGFR monoclonal antibodies in metastatic colorectal cancer patients", Br J Cancer. 2013 Feb 19;108(3):668-75

Editorial

• "Certain miRNAs in gastric juice can be used as biomarkers for the detection of gastric cancer", Junming Guo, Zhejiang Provincial Key Laboratory of Pathophysiology, Department of Biochemistry and Molecular Biology, Ningbo University School of Medicine, Ningbo, China
   
  ""MicroRNAs (miRNAs) play crucial roles during carcinogenesis, but whether miRNAs in gastric juice, which is specific for gastric tissues, can be used as biomarkers of gastric cancer is largely unclear. Patients with gastric cancer had significantly different level of gastric juice miR-21 and miR -106a compared with patients with benign gastric diseases. The areas under ROC curves were up to 0.969 and 0.871 for miR-21 and miR -106a , respectively. Certain miRNAs including miR-21 and miR -106a in gastric juice can be used as biomarkers for the detecting of gastric cancer with a satisfactory specificity and sensitivity".
  (Commentary on:  Cui L et al.: "Gastric juice MicroRNAs as potential biomarkers for the screening of gastric cancer", Med Oncol. 2013 Mar;30(1):365)

Questions and Answers 

• Gastrointestinal Stromal Tumor (GIST) Workshop Summary - with Jeffrey Wayne, Northwestern University Feinberg School of Medicine, Chicago, IL, USA
• Liver Cancer Workshop Summary - with Laura Goff, Vanderbilt-Ingram Cancer Center, Nashville, TN, USA
• Pancreatic Cancer Workshop Summary - with  Andrea Wang-Gillam, Washington University School of Medicine, St. Louis, MO, USA
• Lung Cancer Workshop Summary - with Sai Yendamuri, Roswell Park Cancer Institute, Buffalo, NY, USA  
• Prostate Cancer Workshop Summary - with Donald Trump, Roswell Park Cancer Institute, Buffalo, NY, USA

 Journal of Cancer Science & Therapy  

• Journal of Cancer Science & Therapy has released its latest issue - in collaboration with Senology - Volume 5 Issue 2