- Newsletter

International Senologic and Oncologic  Scientific Community (ISOSC) 

"Connecting specialists worldwide"

June 4, 2013

Editor-in-Chief: Gian Paolo Andreoletti, MD


Senology apps for iPad, iPhone, and Android tablets now available, to provide anytime, anywhere access to Senology contents

Join us on  LinkedInTwitter, Facebook, YouTube, ResearchGateSlideShare, Flickr, and share comments. 

Read Senology Newspaper daily


Senology collaborates with 


Literature Selection


  •  "Use of medications to reduce breast cancer risk", Heidi D. Nelson,  Oregon Health & Science University, Veterans Affairs Medical Center, Portland, OR, USA
    "Our review on use of medications to reduce risk for primary breast cancer indicated that tamoxifen and raloxifene reduced the incidence of invasive breast cancer in women without cancer, but also increased risk for blood clots. Tamoxifen was more effective than raloxifene in reducing breast cancer, but also increased the incidence of endometrial cancer and cataracts.  Both reduced fractures. Adverse effects were more common in older compared to younger women.  Wide-spread use is limited by the adverse effects of medications and inaccurate methods to identify candidates. Medications reduce invasive breast cancer by 7 to 9 cases per 1000 women, assuming 5-years of use.  There are 5 per 1000 fewer cases among women using tamoxifen than raloxifene.  Estrogen receptor positive breast cancers were reduced, but not estrogen receptor negative"
    Commentary on: 
    Nelson H et al.: "Use of medications to reduce risk for primary breast cancer: a systematic review for the u.s. Preventive services task force", Ann Intern Med. 2013 Apr 16;158(8):604-14)

Questions and Answers 


  •   "Guidelines for sentinel lymph node biopsy in contralateral prophylactic mastectomy need to be established to avoid overtreatment" -  Share your opinion on LinkedIn

Fragments of History

Calendar of Events


Literature Selection

Questions and Answers 



Literature Selection



Stay informed....

Recent Advances in Clinical Medicine


                                                                                 Subscribe        Unsubscribe        Contact        Back Issues Newsletter