William
S Halsted (New York, 1852-1922), "The
results of radical operationsfor the cure of carcinoma of the breast", Ann Surg.
July 1907:46(1):1-19":“The Operation - A part of the chest wall should, I believe, be excised in certain cases,
the surgeon bearing in mind always that he is dealing with
lymphatic and not blood metastases and that the slightest
inattention to detail, or attempts to hasten convalescence by
such plastic operations as are feasible only when a restricted
amount of skin is removed, may sacrifice his patient"
-"Study published in The New England Journal of
Medicine: PSA-based screening significantly reduces mortality
from prostate cancer but doesn't affect all-cause mortality"
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"The
use of trastuzumab plus paclitaxel followed by trastuzumab plus
FEC chemotherapy is the standard preoperative systemic therapy for
HER2 positive primary inflammatory breast cancer.
The role of lapatinib in primary inflammatory breast cancer is
unknown despite that there are data suggesting lapatinib may have
a response in trastuzumab-resistant HER2 positive metastatic
breast cancer.For
HER2+ metastatic breast cancer can be treated with lapatinib plus
capecitabine, and trastuzumab plus chemotherapy" (Answer by
Naoto Tada Ueno, Breast
Cancer Translational Research Laboratory, The University of Texas
MD Anderson Cancer Center, Houston, Texas, USA)
